Older women have faced significant disruptions in social connections during the coronavirus disease 2019 pandemic. Whether loneliness increased, or whether a change in loneliness from pre- to intra-pandemic period was associated with mental health during the pandemic is unknown.

Dear Colleagues, It is with great pleasure that we invite you to attend the 7th McMaster International Review Course in Internal Medicine (MIRCIM) which after several years of COVID-19 limitations will again take place in Krakow, Poland, on May 12-14, 2022.

Climate change should be of special concern for the nephrologist as the kidney has a critical role in protecting the host from dehydration, but is also a favorite target of heat stress and dehydration. Here we discuss how rising temperatures and extreme heat events may affect the kidney.

The overall diagnostic yield of massively parallel sequencing (MPS) based-tests in patients with chronic kidney disease (CKD) is around 30% for pediatric cases and 6-30% for adult cases. These figures should encourage nephrologists to frequently use genetic testing as a diagnostic means for their patients, but in reality several barriers appear to hinder the implementation of NGS diagnostics in routine clinical practice.

It is a great pleasure to invite you to join the 6th McMaster International Review Course in Internal Medicine (MIRCIM), which will be held online May 11-June 17, 2021.